nlwxpearo
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Posted: Fri 22:44, 07 Jan 2011 Post subject: Astronaut urine and its impact on the risk of kidn |
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,[link widoczny dla zalogowanych]
Astronaut urine and its impact on the risk of kidney stone
467,[link widoczny dla zalogowanych], p <0001) and urinary oxalate muscle groups did not change the liver. Discussion in space flight, microgravity environment of human adaptation to the physiological changes. These biochemical changes contribute to the urine produced by the formation of calcium kidney stones. Kidney stones will not only affect the health and safety of the astronauts. Also lead to mission failure. 4 Previous studies have shown that urine output can be adjusted relative risk of stone formation, and others in the Pak test, to take moderate physical training, did not add the liquid, the calcium oxalate and uric acid increased the risk of stone formation, which further indicates that the importance of hydration. In vitro studies also showed that urine volume is greater than 2.5L / d, can be improved to reduce the metabolism of calcium oxalate crystals. In addition, recent studies by 1o1 as control samples and 199 primary calcium stone patients, results showed that the urine is a kidney stone formation is a key risk factor. Drink lots of water can reduce the number of stone recurrence. In clinical studies, for the first time in patients suffering from primary calcium-containing kidney stones, the urine output associated with stone formation have been reported in the urine of these patients is lower than ordinary people. In the case does not change the diet, fluid intake can increase the formation of stones in the urinary saturation of salts significantly changed, thereby significantly reducing the recurrence of kidney stones. Choose what kind of fluid intake may also play a role. Instant and decaffeinated coffee may contain as high oxalate stones. The homes of ordinary coffee and caffeine diuretic effect by caffeine can increase the amount of feces, feces diluted solution, which has some protective effect of most researchers believe that increasing the amount of feces is the best liquid water. At present, the urine has not been changed during extravehicular activity research. The study may depend on the establishment of the International Space Station extravehicular activity and the increase in the past, we found that fluid intake during flight than before flight greatly reduced. Continuous 11 ~ 16d: pre-flight 3127 ± 0.211L / d; flight early 1.632 ± 0091L, d; flight late 1704 ± 0.219L / d. A corresponding reduction in urine volume: 1.676 ± O. pre-flight 09L / d; flight early 0.797 ± 0.08L / d {flight late 1.303 ± 0.17L / d. Although urine output increased with the dilution function, but did not reduce the concentration of citrate. The urine output is lower than for those who 2L / d of people, space flight has led to a significant decrease in citrate. The manned space information to analyze the urine of kidney stone formation risk arrest further confirms our previous observation. Urine for kidney stone formation astronaut has a distinct role of osteopontin is an effective inhibitor of calcium oxalate crystals, and with the urine volume is inversely proportional to flight no significant change in osteopontin, but nearly two weeks after their flight level significantly increased. This increase may be due to an increase in urinary crystals or micro-gravity environment, bone involvement on behalf of the anhydride. Although the flight of urine supersaturation increased, but there is no change in orderly transfer of bone may be due to physiological response or no preservatives, preservation of osteopontin caused invalid. Stripping. Laboratory studies of kidney stone inhibitors is still continuing. The urine volume greater than 2L, d astronauts. The occurrence of any type. The risk of kidney stones same as the normal population. In contrast, those less urine D 2L, d of the astronauts, their risk of kidney stones occur before the normal line of 2 times higher risk of post-flight is also. Results of renal risk of thousands of Tong and urine into a negative correlation between the star is further evidence of the importance of the astronauts to improve urine output. These data indicate that the amount of leopard drinking enough water to make the urine more than 2L, d will be reduced in the flight risk of the formation of renal Results stalk tomb. The data in this study clearly shows that the flight before and after the formation of kidney stones increased urine output to reduce the role. We still do not have enough urine in flight data. In theory, the astronauts in flight, drink lots of water to increase urine output, thereby reducing their risk of kidney stones in flight. However, this approach may not be effective, because the basic physiological processes flight may make a higher risk of kidney stone formation in flight at the end. In addition, in flight, low urine output, high calcium, low-acid, low population H in urine, low urinary magnesium will help. Kidney stone formation. Need to minimize the number of ways. Kidney stone formation such as the use of prophylactic medication, such as changes in diet Magnesium citrate. If you find a flight. Learn the causes of stone and effective methods of prevention, increase fluid intake to increase urine output for all the astronauts would be beneficial. Xin Bingmu translated from Avia. SpaceandEnvironmentaIMed. , Vo1.72, No. 4April2001 Wang Yuan School 5
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