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 Posted: Thu 14:29, 10 Mar 2011 Post subject: clarks shoes outlet Plasma tumor necrosis factor ( |
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Plasma tumor necrosis factor (TNF) α and soluble TNF receptor Ⅰ in the clinical significance of acute leukemia
Number, hepatosplenomegaly, LDH was no significant correlation (P values are> O05J (Table 3). Table 3 rI untreated AL patients with clinical features of Contents Note: P for the group compared the prognosis of middle- and the poor and good prognosis,[link widoczny dla zalogowanych], respectively, compared to discuss the study found that those patients TNFu AL were significantly higher than that of normal controls,[link widoczny dla zalogowanych], reported in the literature AL cells autocrine TnI ~ 2. increased the Tm of the AL cells showed why only promote the proliferation of it ? this there is no clear conclusion,[link widoczny dla zalogowanych], probably because: (1) Hui-mediated apoptosis pathway system barriers; (2) Shuai bind, affecting its biological activity. The results show that m level before treatment effect,[link widoczny dla zalogowanych], reflecting the tumor burden showed no significant correlation has nothing to do with the sT ~ TRI, and the relevant reports of malignant lymphoma showed a correlation between the two may be related to differences in detection methods or reagents and sensitivity about the different types of disease as required The results also showed that levels were significantly higher than ANlJ_ and other subtypes,[link widoczny dla zalogowanych], in line with the Wu Xueqiang other 【reported, but the ball flat, and the TN may be due to abnormally high levels of the Ministry of the original Dan naive monocytes to produce related. Therefore, TNFa can be used as ANLL leukemia diagnosis and classification of a secondary target. This study shows that 44 cases of patients with newly diagnosed AL rNFRI almost significantly higher than the water control (P <0O1), consistent with the reported 【J. I often elevated and high differentiation of 197 WBC count, hepatosplenomegaly, LDH correlated significantly higher (P values are <0. 1), and these indicators are related with the tumor burden, elevated plasma against the Ming sTNF ~ I may be the main beam vibration in the Since the secretion of leukemia cells, so handsome I shed the level of plasma can be used as an estimate of tumor load indicator. ImI of plasma levels of AN subtype on 【lIl. literature. primary naive cells for PML-RARa fusion reduced the presence of mT Keegan / Ⅱ expression, thereby preventing TNFu Jazz mediated apoptosis. because l from the membrane receptor, membrane receptor expression when under the withered, the Ji FR levels may also drop accordingly. Therefore, we believe that I was significantly lower than in patients with ANLL in other subtypes (P <0OI), may be relating to. land, sail plasma levels significantly higher than that of other types, mainly due to autocrine role in leukemia cells, since the existence of sub-loop, membrane receptor expression increased by stimulation, malignant cell membrane receptor as easy to fall off, so the performance of coconut l increase. Plasma Ⅱ RI level and the efficacy and prognosis of leukemia with a good correlation shown in this group, CR in newly diagnosed patients I water when a handsome plasma was significantly lower than NR group (P <0.05), chromosome-type related Eucalyptus sTNF ~ l good prognosis group was significantly lower than the poor prognosis group (P <0O1), I better prognosis in patients with the level of M1 was significantly lower than other types of poor prognosis land and other types of patients are higher than can be seen low Ⅵ T indicates a better prognosis. It _-respect may be due to the shedding of membrane receptors, signal transduction to the membrane receptor directly reduced, not apoptotic signal transduction; On the other hand nFRl competitive binding and membrane receptor TN, inhibit the biological effects on target cells, resulting in the tumor cells to escape immune surveillance. rmI what, exactly, on the AL cell regulation, to be further explored:
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