nlwxpearo
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 Posted: Thu 22:34, 17 Mar 2011 Post subject: Isosorbide dinitrate , Norvasc , metoprolol combin |
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Isosorbide dinitrate, Norvasc,[link widoczny dla zalogowanych], metoprolol combined treatment of angina pectoris tired
Therapy. At present, there are three types of drugs - nitrates,[link widoczny dla zalogowanych], blockers and calcium antagonists at one. Clinical in a single, two joint or triple therapy. According to three different mechanisms of drug action, multi-tendency to combination therapy. ... To observe the effect of triple therapy, through their own symptoms before and after treatment, were indicators of the dynamic electrocardiogram. 1 1.1 General situation of clinical data: The 33 patients were selected from our hospital in May 1997 ~ March 1999 outpatient and inpatient. 25 patients were male. 8 females, aged 50 to 80 years, mean 58 ± 9 years old. Exertional angina were Ⅲ Ⅱ a satin patients. In which 12 patients with hypertension, hyperlipidemia 20,[link widoczny dla zalogowanych], down from 6 cases of diabetes. ≥ Ⅱ satin heart function (NYHA Standards Committee amended in 1994). 【Quiet state heart rate Ⅱ 'atrioventricular block in patients with no choice over. 12 Methods based on clinical symptoms and blood pressure changes (both control normal range) its population medicine. Isosorbide dinitrate 15 - 45nk ~ / d, administered three times; Norvasc 5 ~ l0 Ⅱ, d, one dose; metoprolol 25 ~ 150mg / d,[link widoczny dla zalogowanych], at the second administration. Hyperlipidemia, diabetes, symptomatic treatment for 8 weeks after treatment underwent dynamic electrocardiography. Addition to regular life in patients with B requirements. Also developed some moving target,[link widoczny dla zalogowanych], strict ST segment depression criteria ¨ J, the 2 Results after treatment episodes, duration was less alkaline. Dynamic ECG indicators in Table 1. Check the indicators around the table l Holter average (; ± cow / / can be seen from the table. Triple the number of angina pectoris after treatment, 24h average heart rate, ST segment depression in the average rate, ST segment depression at all times the total average reduction in body <0.01, statistically significant. 3 Discussion intravenous nitrates first expansion, so change thy blood less, left ventricular end diastolic volume and pressure of the low base, followed by left ventricular systolic tension reduction. myocardial oxygen reduction . Second expansion of the arterial system, to reduce afterload. Finally, expansion of coronary Mi, increasing blood flow. the main side effects are headache, decreased blood pressure resistance. blockers can reduce the population of a quiet and exercise heart rate, lower blood pressure and reducing ventricular contraction rate. side effects caused by the negative inotropic left ventricular volume increase. calcium antagonist Jing expansion of the role of peripheral vascular and coronary artery. denitrification adjacent pyridine benzene increased heart rate reflex is easy, diltiazem and verapamil on the conduction system and myocardial contraction a great impact force Hj, select the role of relaxation lasting Norvasc, which greatly reduced side effects through the combination of three drugs. both synergies and reducing the side effects (offset), improve efficacy, but also to reduce the dose of various drugs. The three dose groups were less than the amount of data, therefore, the control points through the group discount. In the premise of strictly indications, treatment should be combined three types of exertional angina medication. to improve the efficacy for reducing coronary heart disease angioplasty and revascularization therapy. improve the quality of life. 4
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