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PostPosted: Fri 7:37, 11 Mar 2011    Post subject: new balance outlet Five Principles _2542 old drug

Five Principles of older drugs


Salt, B blockers and calcium antagonists. 3. Antiarrhythmic drugs: the peak incidence of sudden cardiac death in the 7: OO ~ 11: OO, the second peak at 17: OO ~ 18:00; peak incidence of ventricular arrhythmia was 9:00 ~ 10: O0,[link widoczny dla zalogowanych], advocate at night B blockers to control sympathetic hyperactivity next morning. Conduction system degeneration, often elderly, the use of B blockers or dihydropyridine calcium antagonists should be avoided at night heart rate is too slow. 4. Cardiac drugs: heart failure patients cedilanid,[link widoczny dla zalogowanych], digoxin sensitivity to 4: OO highest, higher than any other time of 10 to 20 times,[link widoczny dla zalogowanych], thus using the conventional dose of highly toxic after midnight. 5. Hormonal and non-steroidal anti-inflammatory drugs: human adrenal cortex hormone secretion was low daytime high night, the morning service not interfere with the secretion of Dayton rhythm, can increase efficacy and reduce side effects. Slow excretion of sodium salicylate in the morning, the evening fast excretion, such as 3 times the traditional medication sharing is precisely the minimum plasma concentration early in the morning is not conducive to ease morning joint symptoms. Rational use of the morning program is to increase the dose, slightly longer treatment intervals,[link widoczny dla zalogowanych], the amount of less than normal night, the best medicine in the middle of the night 1. Can also be indomethacin 25mg, 3 times / d, 100mg change clothes after dinner Dayton, efficacy and better,[link widoczny dla zalogowanych], and easily tolerated. 6. Other drugs: ginseng, royal jelly and other supplements should be taken empty stomach to increase the absorption and efficacy. Magnesium sulfate, anthelmintic empty stomach, to quickly reach a gut play a role. Gastric motility drugs, stomachic, Zhuxiaohuayao, antacids, choleretic drugs and astringent drugs such as application of 15 ~ 30min before a meal, that will help drug effect. Non-steroidal anti-inflammatory drugs, ferrous sulfate, ammonium chloride, hydrochloric acid and other irritating substances 30min after the meal should be used to reduce gastrointestinal mucosal damage. Cholesterol synthesis overnight fast, gastric acid secretion and more bedtime Hz blockers or statins can play the biggest role in the drug. Before going to bed with a blocker first, the symptoms of benign prostatic hyperplasia significantly at night, the second is to avoid the occurrence of orthostatic hypotension. If the slow onset of conduction (8 ~ 12h), medication before going to bed, next morning defecation. Fifth, the principle of suspension of medication during the treatment in the elderly should be closely observed, in the event of any new symptoms, including physical, emotional awareness or symptoms, should consider ADR or disease progression. Both situations will be handled completely different, the former drug withdrawal, the latter dosing. Therefore, drugs used for patients should be carefully reviewed and evaluated as to check for potential infections or metabolic changes and so on. When the suspected ADR, the withdrawal period in custody, said the suspension of drug (medicationuntria1). . This can remind physicians to understand the elderly are often the drugs used, when new symptoms to consider the possibility of ADR. Such as the reduction or withdrawal symptoms improved or disappeared, that is the ADR. Sometimes elderly people hospitalized due to ADR after admission as long as the drugs used to stop the original, his condition improved markedly. For the elderly a new drug symptoms of drug withdrawal benefit significantly more than benefit increases, so the suspension of drug use is the simplest of modern gerontology, one of the most effective interventions, it is worth attention. As the physician Hippocrates pointed out that: no treatment is sometimes a good therapy, fully stressed the importance of ADR in clinical importance.
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