nlwxpearo
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Location: England
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 Posted: Mon 10:12, 21 Mar 2011 Post subject: Serum of patients with Graves endogenous digitalis |
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Serum of patients with Graves endogenous digitalis factor in
ormone) for the same factor. Most organizations EDF inhibit Na. K. 【 ATP activity . Myocardial membrane Na. K. EDF ATP enzyme is inhibited , the intracellular negative charge to reduce myocardial cell depolarization, reduction of intracellular ca2 flow ,[link widoczny dla zalogowanych], myocardial contractility increase. Graves increased blood volume in patients with total body high-capacity load of the heart produced ,[link widoczny dla zalogowanych], increased cardiac work ,[link widoczny dla zalogowanych], leading to cardiac hypertrophy. Graves of cardiac contractility and diastolic relaxation rates show an increase , but the exchange of experience ● ● heart can only work limited ,[link widoczny dla zalogowanych], so the reserve decreased. High capacity load, reduced cardiac contractility reserve three common causes of heart failure and tachycardia _4 ]. This article shows hyperthyroid Graves disease and heart disease Graves disease group and the group without complications ,[link widoczny dla zalogowanych], EDF was significantly higher , P <0.01. Speculated that there are 2 possible : ① in the early heart disease hyperthyroidism , because the body compensatory mechanisms , resulting in elevated serum EDF to enhance myocardial contractility and reduce cardiac stress ; long-term elevated serum EDF force of myocardial contraction reserve further Reduced, increasing heart failure, while the patient cardiac digitalis substances on high sensitivity , resulting in poor treatment . ② higher long-term thyroid hormone , hyperthyroidism without proper treatment, with concomitant increase in EDF , can promote the occurrence of hyperthyroid heart disease ? above speculation needs further study. Graves disease associated with periodic paralysis Graves disease group and the group without complications , the serum was no significant difference between EDF , suggesting that in the Graves patients , serum EDF and the incidence of periodic paralysis was no significant relationship. In short, the active treatment of hyperthyroidism , and in EDF or eliminate excessive body to improve cardiac function in hyperthyroid heart has a certain value.
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