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Posted: Tue 23:53, 15 Mar 2011 Post subject: Preparation of famotidine pills and content of the |
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Preparation of famotidine pills and content of the dissolution study
Amount of goods , made to match with the flow containing 0.2mg per lml of the solution ,belstaff milano, shake,timberland shoes, that is, too . Preparation of the test solution of 20 pills to take for the test materials , and research uniform, accurately weighed amount (equivalent to famotidine 20mg), set 100ml flask,ghd piastre, add the mobile phase dissolved and diluted to volume, filtered , as for Test solution. According to high performance liquid chromatography (China Volume II Appendix VD) determined the precise amount of solution of 20l, high performance liquid chromatograph , record the chromatogram , according to external standard method with peak area calculation,ugg stiefel, which was shown in Table 11 . Table 11 Results of determination of famotidine pills 5 Conclusion and discussion paper on the basis of a large number of tests designed prescriptions , and the dissolution of famotidine pills and drug content were examined. The results are as follows : 5.1 weight difference made to meet the requirements of famotidine pills . Roundness of pills and content uniformity were good. 5.2 The dissolution experiments show that the pills as a solid dispersion agent,p90x workout schedule, effectively accelerated the release of famotidine , an increase of drug solubility . Determination experiment shows that this method were accurate content of famotidine pills . While a smaller pill weight also taking more convenient. Compared with other formulations , famotidine pills process is simple , low cost, quality control is easy, has practical value. |
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